Article
Genetic variations in nucleotide excision repair pathway genes and hepatoblastoma susceptibility.
International journal of cancer - 1 Nov 2021
Zhuo Zhenjian, Miao Lei, Hua Wenfeng, Chen Huitong, Yang Zhonghua, Li Yong, Zhang Jiao, Li Suhong, Cheng Jiwen, Li Li, Xia Huimin, He Jing
Abstract excerpt
The etiology of hepatoblastoma is largely unknown due to the rarity of this disease. Nucleotide excision repair (NER), a versatile system in repairing DNA damage, is highly implicated in carcinogenesis. However, it remains unclear whether single nucleotide polymorphisms (SNPs) of genes in the NER pathway are related to hepatoblastoma risk. A total of 313 Chinese children diagnosed with hepatoblastoma and 1446...
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