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Genomic and epigenomic integrative subtypes of renal cell carcinoma in a Japanese cohort

16 Dec 2023

Abstract excerpt

Renal cell carcinoma (RCC) comprises several histological types characterised by different genomic and epigenomic aberrations; however, the molecular pathogenesis of each type still requires further exploration. We perform whole-genome sequencing of 128 Japanese RCC cases of different histology to elucidate the significant somatic alterations and mutagenesis processes. We also perform transcriptomic and...

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PMID: 38104198
DOI: 10.1038/s41467-023-44159-1

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