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Article

Cardiomyocyte derived extracellular mitochondria in activation of macrophages during oxidative stress.

Cardiovascular research - 26 Mar 2026

Shrestha Lenee, Gu Haiwei, Satterlee Taylor, He Suizi, Chen Qin M

Abstract excerpt

AIMS: Mitochondria serve as central hubs for aerobic metabolism and regulators of cell fate. Damage to mitochondria induced by oxidative stress contributes to cardiac injury. We investigate whether oxidative stress causes the release of mitochondria into the extracellular space and whether these extracellular mitochondria (EM) mediate the detrimental effect of oxidative stress. METHODS AND RESULTS: AC16...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41556135
DOI: 10.1093/cvr/cvag014
PMCID: PMC13020540

Genes

CD163

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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