Article
A Cross-Tissue Transcriptome-Wide Association Study Reveals Novel Susceptibility Genes for Inflammatory Bowel Disease.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 31 Jan 2026
Zhou Yang, Guo Jintao
Abstract excerpt
Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), is an autoimmune disease with a strong genetic component. Although genome-wide association studies (GWAS) have identified multiple risk loci, the underlying causal genes and biological mechanisms remain predominantly elusive. GWAS data for IBD, UC, and CD were obtained from the FinnGen R10 dataset and integrated with...
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