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Article

Single-Cell Multimodal Profiling Reveals a Novel CD26+ Fibroblast Subpopulation in Atherosclerosis-Brief Report.

Arteriosclerosis, thrombosis, and vascular biology - 1 Aug 2025

Bashore Alexander C, Coronel Johana, Xue Chenyi, Zhu Lucie Y, Reilly Muredach P

Abstract excerpt

BACKGROUND: Atherosclerosis involves complex interactions between lipids, immune cells, vascular smooth muscle cells, and fibroblasts within the arterial wall. While significant advances in single-cell technologies have shed light on the roles of immune cells and vascular smooth muscle cells in plaque development, fibroblasts remain underexplored, leaving critical gaps in understanding their contributions to...

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Identifiers

PMID: 40501383
DOI: 10.1161/ATVBAHA.124.322370
PMCID: PMC13274626

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