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Article

STAM1-deficient mice exhibit an attention-deficit/hyperactivity disorder-like phenotype.

Biochemical and biophysical research communications - 5 Feb 2026

Fujiwara Hironori, Nakagawasai Osamu, Suzuki Shuhei, Tajima Hirohisa, Takahashi Kohei, Onogi Hiroshi, Sakuma Wakana, Tan-No Koichi, Murata Kazuko

Abstract excerpt

Despite recent abundant studies on animal models of attention-deficit/hyperactivity disorder (ADHD), a complete model remains unestablished. In this study, we investigated the potential of STAM1-deficient mice as a new animal model for ADHD. STAM1-deficient mice escaped from a high platform significantly faster than wild-type mice, indicating ADHD-like impulsivity. Low anxiety-like behavior in STAM1-deficient...

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Attention Deficit Disorder with Hyperactivity
Clozapine
Dopamine
Endosomal Sorting Complexes Required for Transport
Haloperidol

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Inbred C57BL

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PMID: 41520568
DOI: 10.1016/j.bbrc.2026.153264

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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