Article
A new mouse model of ADHD for medication development.
Scientific reports - 20 Dec 2016
Majdak Petra, Ossyra John R, Ossyra Jessica M, Cobert Adam J, Hofmann Gabrielle C, Tse Stephen, Panozzo Brent, Grogan Elizabeth L, Sorokina Anastassia, Rhodes Justin S
Abstract excerpt
ADHD is a major societal problem with increasing incidence and a stagnant track record for treatment advances. A lack of appropriate animal models has partly contributed to the incremental advance of this field. Hence, our goal was to generate a novel mouse model that could be useful for ADHD medication development. We reasoned that hyperactivity is a core feature of ADHD that could easily be bred into a...
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