Genetic Insights Into the Central Role of Serine β-Lactamase-Like Protein in Lipid Metabolism, Metabolic Syndrome, and Chronic Kidney Disease.

Abstract excerpt

Serine β-lactamase-like protein (LACTB), a mitochondrial protease, has incompletely characterized roles in metabolic pathways. We employed Mendelian randomization to investigate LACTB's causal relationships with lipid metabolism, metabolic syndrome (MetS), and chronic kidney disease (CKD). We performed a comprehensive Mendelian randomization (MR) analysis using genome-wide association study summary statistics....

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to beta-Lactamases
• Share to Genome-Wide Association Study