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Causal relationship between branched-chain amino acids and leukemia risk: insights from a two-sample Mendelian randomization study.

Hematology (Amsterdam, Netherlands) - 1 Dec 2024

Chen Shupeng, He Guilian, Zhang Meiling, Tang Nana, Zeng Yingjian

Abstract excerpt

BACKGROUND: Branched-chain amino acids (BCAAs), including leucine, isoleucine, and valine, are essential amino acids involved in protein synthesis, energy metabolism, and immune regulation. While BCAAs are known to influence cancer biology, their role in leukemia remains unclear. This study employs Mendelian randomization (MR) analysis to explore the causal relationship between BCAA levels and four leukemia...

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Share to Amino Acids, Branched-Chain
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39663823
DOI: 10.1080/16078454.2024.2433904

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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