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Article

Aminotransferases as causal factors for metabolic syndrome: A bidirectional Mendelian randomization study.

PloS one - 1 Jan 2024

Lingyu Meng, Hongguang Li, Mingdong Zhang, Na Li, Yahui Liu

Abstract excerpt

BACKGROUND: Circulating aminotransferases (ALT and AST) have been used as biomarkers for liver injury. The causal relationships between aminotransferases and metabolic syndrome remain ambiguous. METHODS: We conducted bidirectional and multivariable Mendelian randomization (MR) analyses between aminotransferases and traits related to metabolic syndrome using genetic variants obtained from genome-wide association...

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Identifiers

PMID: 38662679
DOI: 10.1371/journal.pone.0302209
PMCID: PMC11045112

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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