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Article

Genetic landscape of pediatric acute myeloid leukemia in Taiwan.

Scientific reports - 7 Jan 2026

Cheng Zhongshan, Yu Sung-Liang, Yu Chih-Hsiang, Chang Ti-Cheng, Chang Ya-Hsuan, Jou Shiann-Tarng, Lu Meng-Yao, Lin Kai-Hsin, Chang Hsiu-Hao, Chou Shu-Wei, Lin Ze-Shiang, Kuo Chieh-Wen, Liew Phooi-Theng, Du Chia-Jui, Lin Chien-Yu, Ni Yu-Ling, Chen Hsuan-Yu, Lin Dong-Tsamn, Lin Shu-Wha, Wu Gang, Pui Ching-Hon, Yang Yung-Li

Abstract excerpt

The international consensus classification or the World Health Organization classifications underrepresented driver alterations enriched in pediatric acute myeloid leukemia (AML). To address this, we retrospectively characterized the genomic landscape of 105 pediatric patients with AML of East Asian ancestry using transcriptome and whole-exome sequencing (WES). In addition to the common recurrent fusions such as...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41495268
DOI: 10.1038/s41598-025-34152-7
PMCID: PMC12855802

Genes

FLT3
RUNX1
CBFB
KMT2A
MLLT10
MYH11
NUP98
PICALM
RUNX1T1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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