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Article

Data-driven approaches to advance research and clinical care for pediatric cancer.

Biochimica et biophysica acta. Reviews on cancer - 1 Aug 2021

Gout Alexander M, Arunachalam Sasi, Finkelstein David B, Zhang Jinghui

Abstract excerpt

Pediatric cancer is a rare disease with a distinct etiology and mutational landscape compared with adult cancer. Multi-omics profiling of retrospective and prospective cohorts coupled with innovative computational analysis have been instrumental in uncovering mechanisms of tumorigenesis and drug resistance that are now informing pediatric cancer clinical therapy. In this review we present the major data resources...

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PMID: 34051287
DOI: 10.1016/j.bbcan.2021.188571

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