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Reduced levels of N6-methyladenosine in RNA of peripheral blood mononuclear cells from patients with Alzheimer's disease

2023-03-24

Abstract excerpt

<title>Abstract</title> <p><bold>Background </bold>Alzheimer's disease (AD) is the leading cause of dementia, yet its underlying causes remain unknown. Increasing evidence supports a role for epigenetic modifications in AD pathogenesis. N6-methyladenosine (m6A), the most common RNA modification, is critical for learning and memory, and its abnormal presence has been observed in the brains of AD patients and anima...

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Literature Corpus work
4e6e785f-5ab7-5d14-9c7a-242096d0323f
DOI
10.21203/rs.3.rs-2699617/v1
Open publication

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Reduced levels of N6-methyladenosine in RNA of peripheral blood mononuclear cells from patients with Alzheimer's diseaseDOI 10.21203/rs.3.rs-2699617/v1
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