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Article

Association between pesticide exposure and breast cancer risk: a two-sample Mendelian randomization study.

International archives of occupational and environmental health - 23 Dec 2025

Sang Yuchao, Huang Dongqin, Chen Xintan, Lin Xinjian, Li Mingmei, Xie Chengwei, Su Yuchao, Chen Baojia, Hu Nanping

Abstract excerpt

BACKGROUND: Several observational studies have suggested a link between pesticide exposure and breast cancer, but the causal relationship remains debated. METHODS: This study employed a two-sample Mendelian randomization (MR) approach to explore the potential causal link between pesticide exposure and breast cancer risk. Genetic instruments for pesticide exposure were identified from a genome-wide association...

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PMID: 41432777
DOI: 10.1007/s00420-025-02192-1

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