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Article

Heavy metal exposure and cancer risk: Findings from a Mendelian randomization study.

Toxicology letters - 1 Mar 2026

Qin Shuang, Xie Longhui, Lan Jianwei, Yang Yang, Diao Wuliang, Ning Yinkuan

Abstract excerpt

BACKGROUND: Epidemiological evidence has established associations between heavy metal exposure and increased risks of various cancers. However, causality remains difficult to establish in conventional observational studies due to residual confounding and reverse causation. Mendelian randomization (MR) could overcome these limitations by using genetic variants as instrumental variables to strengthen causal...

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Identifiers

PMID: 41638406
DOI: 10.1016/j.toxlet.2026.111848

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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