Article
Genetic susceptibility to breast cancer increases the risk of neutropenia and agranulocytosis: insights from Mendelian randomization.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer - 29 Jun 2024
Wei Changlong, Zhang Gongyin, Li Changwang, Zeng Jinsheng
Abstract excerpt
PURPOSE: The causal relationship between breast cancer and its estrogen receptor (ER) subtypes and neutropenia and agranulocytosis is unclear. METHODS: In two-sample Mendelian randomization (MR), we used inverse variance weighting (IVW), Bayesian weighted MR (BWMR), MR-Egger, weighted median, simple mode, and weighted mode methods to analyze causality for ER-positive breast cancer, ER-negative breast cancer,...
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