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Article

Propylparaben Promotes Estrogen Receptor-Positive Breast Cancer Risk through PIK3R1: A Comprehensive Integrative Study

2025-10-31

Abstract excerpt

<title>Abstract</title> <p>Background Propylparaben (PP), a preservative in cosmetics, food, and pharmaceuticals, is a potential endocrine disruptor. However, the molecular mechanisms linking PP exposure to estrogen receptor-positive (ER⁺) breast cancer (BC) remain unclear. Methods This study integrated network toxicology with The Cancer Genome Atlas (TCGA) data to identify carcinogenic targets of PP. Protein-pro...

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Literature Corpus work
0622fbcd-6a9c-5877-932a-05c32a415a37
DOI
10.21203/rs.3.rs-7400738/v1
Open publication

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Propylparaben Promotes Estrogen Receptor-Positive Breast Cancer Risk through PIK3R1: A Comprehensive Integrative StudyDOI 10.21203/rs.3.rs-7400738/v1
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