Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variation in nucleotide excision repair pathway genes, pesticide exposure and prostate cancer risk.

Carcinogenesis - 1 Feb 2012

Barry Kathryn Hughes, Koutros Stella, Andreotti Gabriella, Sandler Dale P, Burdette Laurie A, Yeager Meredith, Beane Freeman Laura E, Lubin Jay H, Ma Xiaomei, Zheng Tongzhang, Alavanja Michael C R, Berndt Sonja I

Abstract excerpt

Previous research demonstrates increased prostate cancer risk for pesticide applicators and pesticide manufacturing workers. Although underlying mechanisms are unknown, human biomonitoring studies indicate increased genetic damage (e.g. chromosomal aberrations) with pesticide exposure. Given that the nucleotide excision repair (NER) pathway repairs a broad range of DNA damage, we evaluated interactions between...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cohort Studies
Share to DNA Repair

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Follow-Up Studies

Share to Homozygote

Share to Logistic Models

Share to Odds Ratio

Share to Pesticides

Share to Prostatic Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 22102698
DOI: 10.1093/carcin/bgr258
PMCID: PMC3271261

Genes

CDK7
ERCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variation in nucleotide excision repair pathway genes, pesticide exposure and prostate cancer risk.PMID 22102698Read ↗

Genetic variation in base excision repair pathway genes, pesticide exposure, and prostate cancer risk.Semantic proximity Read ↗

Pesticide exposure and inherited variants in vitamin d pathway genes in relation to prostate cancer.Semantic proximity Read ↗

Joint associations between established genetic susceptibility loci, pesticide exposures, and risk of prostate cancer.Semantic proximity Read ↗

Genetic susceptibility loci, pesticide exposure and prostate cancer risk.Semantic proximity Read ↗

Pesticide use modifies the association between genetic variants on chromosome 8q24 and prostate cancer.Semantic proximity Read ↗

Xenobiotic-metabolizing gene variants, pesticide use, and the risk of prostate cancer.Semantic proximity Read ↗

Exploring the Utility of Expanded Clinical Exome Sequencing in Cancer Patients with Pesticide Exposure: Insights from Blood SamplesSemantic proximity Read ↗

Genetic variants in xenobiotic detoxification enzymes, antioxidant defenses and hormonal pathways as biomarkers of susceptibility to prostate cancer.Semantic proximity Read ↗

Pesticides, gene polymorphisms, and bladder cancer among Egyptian agricultural workers.Semantic proximity Read ↗

Host factors and genetic susceptibility: a paradigm of the conundrum of pesticide exposure and cancer associations.Semantic proximity Read ↗

Polymorphisms in ERCC1, ERCC4 and ERCC5 genes as biomarkers of susceptibility for pesticide-induced DNA damage in North-West Indian agricultural workers.Semantic proximity Read ↗

DNA methylation alterations in response to pesticide exposure <i>in vitro</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.