Article
Preemptive NUDT15 Genotyping and Its Impact on Febrile Neutropenia in Pediatric Patients With Acute Lymphoblastic Leukemia in Taiwan.
Journal of pediatric hematology/oncology - 1 Jan 2026
Cheng Chiao-Yu, Wang Der-Shiun, Yu Chih-Hsiang, Jou Shiann-Tarng, Lin Chien-Yu, Lin Kai-Hsin, Lu Meng-Yao, Chang Hsiu-Hao, Chou Shu-Wei, Du Chia-Jui, Ni Yu-Ling, Lin Dong-Tsamn, Lin Shu-Wha, Chen Hsuan-Yu, Yang Yung-Li
Abstract excerpt
This study investigated whether preemptive NUDT15 genotyping can reduce episodes of febrile neutropenia during the continuation phase of acute lymphoblastic leukemia (ALL) treatment. This retrospective cohort study enrolled 243 children with ALL who were treated according to the Taiwan Pediatric Oncology Group protocol at the National Taiwan University Hospital. The patients were divided into those who underwent...
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