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Article

Integrin is required for basement membrane crossing and branching of an invading intracellular tube.

Development (Cambridge, England) - 1 Jan 2026

Meyer Lauren N, Hertel Michael, Nance Jeremy

Abstract excerpt

The narrowest biological tubes are formed by cells that hollow to form an intracellular lumen. Here, we examine early lumenogenesis of the C. elegans excretory cell, which branches to form an H-shaped intracellular tube spanning the length of the worm. Using genetically paralyzed embryos to freeze movement, we describe lumen initiation and branching for the first time using time-lapse fluorescence microscopy. We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41321174
DOI: 10.1242/dev.204893
PMCID: PMC12710419

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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