Article
Neuronal migrations and axon fasciculation are disrupted in ina-1 integrin mutants.
Neuron - 1 Jul 1997
Baum P D, Garriga G
Abstract excerpt
Integrins are heterodimeric cell surface receptors implicated in cell adhesion and signaling. Our analysis of C. elegans ina-1 alpha integrin mutants provides the first genetic evidence that migrating neurons require integrins. Mosaic analysis and expression studies show that ina-1 acts autonomou...
Topics
- Animals
- Axons
- Cell Movement
- Integrins
- Mutation
- Neurons