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Building bridges for oocyte growth: regulation of C. elegans germline architecture and function by oriented cell divisions

8 Aug 2025

Abstract excerpt

In most animals, the growth of oocytes depends on the delivery of cytoplasm from other germ cells ("nurse" cells) via cytoplasmic bridges. In some cases, such as in mice and Drosophila, these bridges are formed via incomplete cytokinesis and connect the germ cells to the oocyte directly. In other animals, like the nematode Caenorhabditis elegans (C. elegans), germ cells are connected to an anucleate core of...

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PMID: 40784521
DOI: 10.1016/j.ydbio.2025.08.005

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