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Article

Integrin acts upstream of netrin signaling to regulate formation of the anchor cell's invasive membrane in C. elegans.

Developmental cell - 1 Aug 2009

Hagedorn Elliott J, Yashiro Hanako, Ziel Joshua W, Ihara Shinji, Wang Zheng, Sherwood David R

Abstract excerpt

Integrin expression and activity have been strongly correlated with developmental and pathological processes involving cell invasion through basement membranes. The role of integrins in mediating these invasions, however, remains unclear. Utilizing the genetically and visually accessible model of anchor cell (AC) invasion in C. elegans, we have recently shown that netrin signaling orients a specialized invasive...

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Identifiers

PMID: 19686680
DOI: 10.1016/j.devcel.2009.06.006
PMCID: PMC2729287

Genes

INA
DCC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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