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Article

Fine-Scale Mapping of HLA-C Haplotype Structural Diversity Using SNP Crossover Regions Flanked by Transposable Element Markers in Homozygous Cell Lines.

International journal of immunogenetics - 1 Apr 2026

Kulski Jerzy K

Abstract excerpt

BACKGROUND/OBJECTIVES: The human major histocompatibility complex (MHC) is characterized by extreme polymorphism, with HLA-C contributing to pathogen defence, disease susceptibility, and transplantation outcomes. Beyond allelic diversity, and variation, the evolutionary restructuring of haplotypes influences functional diversity across the region. This study analysed HLA-C haplotypes in the context of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41317107
DOI: 10.1111/iji.70029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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