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Article

Immune Cell Type-Specific DNA Methylation Regions Associate With 24-Hour Blood Pressure Regulation in Black People.

Journal of the American Heart Association - 17 Mar 2026

Pan Xiaoqing, Yang Yifan, Li Jialiang, Kidambi Srividya, Liang Mingyu, Li Yingchuan, Liu Pengyuan

Abstract excerpt

BACKGROUND: DNA methylation and immune cells have been linked to blood pressure (BP) regulation and the development of hypertension. However, the immune cell profiles and the cell type-specific DNA methylation associated with BPs remain unclear. METHODS: This study evaluates the 19 cell type deconvolution algorithms using reduced representation bisulfite sequencing data, comparing them to in silico mixtures...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41294148
DOI: 10.1161/JAHA.125.043163
PMCID: PMC13055841

Genes

CD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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