Article

Genome-wide mapping of sex-associated autosomal DNA methylation in major blood cell types

2025-10-15

Abstract excerpt

<h4>ABSTRACT</h4> Sex differences shape human physiology and disease risk, yet their autosomal epigenetic basis remains incompletely understood. Using whole genome bisulfite sequencing data from iMETHYL database (∼100 adults) across three purified blood cell types (CD4⁺ T cells, monocytes, neutrophils), we performed comprehensive mapping of cell-type specific sex-associated DNA methylation. Using genome-wide Z -...

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Literature Corpus work: a3a4bb57-7894-5148-a889-5c50e1d374c1
DOI: 10.1101/2025.10.14.682299

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