Article
Unique Associations of DNA Methylation Regions With 24-Hour Blood Pressure Phenotypes in Black Participants.
Hypertension (Dallas, Tex. : 1979) - 1 Apr 2022
Roberts Michelle L, Kotchen Theodore A, Pan Xiaoqing, Li Yingchuan, Yang Chun, Liu Pengyuan, Wang Tao, Laud Purushottam W, Chelius Thomas H, Munyura Yannick, Mattson David L, Liu Yong, Cowley Allen W, Kidambi Srividya, Liang Mingyu
Abstract excerpt
BACKGROUND: Epigenetic marks (eg, DNA methylation) may capture the effect of gene-environment interactions. DNA methylation is involved in blood pressure (BP) regulation and hypertension development; however, no studies have evaluated its relationship with 24-hour BP phenotypes (daytime, nighttime, and 24-hour average BPs). METHODS: We examined the association of whole blood DNA methylation with 24-hour BP...
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