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Article

Causal relationship between circulating micronutrient levels and bipolar disorder: A Mendelian randomization study.

Medicine - 19 Dec 2025

You Ting, Yang Xiuwen, Feng Huaili, Liu Zhaoyi, Chen Chengzhi, Qiu Jingfu

Abstract excerpt

Bipolar disorder (BD) is a significant mental health condition characterized by alternating episodes of mania and depression, impacting millions worldwide. Genetic factors are known to play a major role in BD, but the influence of circulating micronutrient levels remains unclear. Two-sample Mendelian randomization (MR) and multiple MR were used to assess the impact of 15 circulating micronutrients, including...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41431023
DOI: 10.1097/MD.0000000000046691
PMCID: PMC12727273

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