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Article

Causal associations between immune cells and psychiatric disorders: a bidirectional mendelian randomization analysis.

Naunyn-Schmiedeberg's archives of pharmacology - 1 Jul 2025

Li Yi, Sun Guanchao, Cui Yingshu, Ji Shuaifei, Kan Ting

Abstract excerpt

Extensive researches illuminate a potential interplay between immune traits and psychiatric disorders. However, whether there is the causal relationship between the two remains an unresolved question. We conducted a two-sample bidirectional mendelian randomization by utilizing summary data of 731 immune cell traits from genome-wide association studies (GCST90001391-GCST90002121)) and 11 psychiatric disorders...

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Identifiers

PMID: 39878811
DOI: 10.1007/s00210-025-03818-4

Genes

CD14
CCR2
CD27
CD38
PGC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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