Article
Pharmacogenomic Insights: The Role of CYP2D6 Allelic Variants in Drug Metabolism Among COVID-19 Patients With Comorbidities.
In vivo (Athens, Greece) - 1 Jan 2025
Özen Mert, Oskay Alten, Türkçüer Ibrahim, Yilmaz Atakan, Seyit Murat, Adali Yasemin, Çakmak Vefa, Köseler Aylin
Abstract excerpt
BACKGROUND/AIM: Drug metabolism and thus drug efficacy can be affected by individual differences in cytochrome P450 2D6 enzyme (CYP2D6) due to genetic polymorphism in its gene. In this study, we aimed to investigate CYP2D6 allelic variants in drug metabolism among patients with COVID-19 with comorbidities. PATIENTS AND METHODS: This prospective case-control study, approved by the Pamukkale University Ethics...
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- Humans
- Cytochrome P-450 CYP2D6
- COVID-19
- Female
- Male
- Middle Aged