Article
Pharmacogenomic landscape of COVID-19 therapies from Indian population genomes.
Pharmacogenomics - 1 Jul 2021
Sahana S, Sivadas Ambily, Mangla Mohit, Jain Abhinav, Bhoyar Rahul C, Pandhare Kavita, Mishra Anushree, Sharma Disha, Imran Mohamed, Senthivel Vigneshwar, Divakar Mohit Kumar, Rophina Mercy, Jolly Bani, Batra Arushi, Sharma Sumit, Siwach Sanjay, Jadhao Arun G, Palande Nikhil V, Jha Ganga Nath, Ashrafi Nishat, Mishra Prashant Kumar, Vidhya A K, Jain Suman, Dash Debasis, Kumar Nachimuthu Senthil, Vanlallawma Andrew, Sarma Ranjan Jyoti, Chhakchhuak Lalchhandama, Kalyanaraman Shantaraman, Mahadevan Radha, Kandasamy Sunitha, Devi Pabitha, Rajagopal Raskin Erusan, Ramya J Ezhil, Devi P Nirmala, Bajaj Anjali, Gupta Vishu, Mathew Samatha, Goswami Sangam, Prakash Savinitha, Joshi Kandarp, Kumla Meya, Sreedevi S, Gajjar Devarshi, Soraisham Ronibala, Yadav Rohit, Devi Yumnam Silla, Gupta Aayush, Mukerji Mitali, Ramalingam Sivaprakash, Binukumar B K, Sivasubbu Sridhar, Scaria Vinod
Abstract excerpt
Aim: Numerous drugs are being widely prescribed for COVID-19 treatment without any direct evidence for the drug safety/efficacy in patients across diverse ethnic populations. Materials & methods: We analyzed whole genomes of 1029 Indian individuals (IndiGen) to understand the extent of drug-gene (pharmacogenetic), drug-drug and drug-drug-gene interactions associated with COVID-19 therapy in the Indian population....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.