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Pharmacogenomic insights in psychiatric care: uncovering novel actionability, allele-specific CYP2D6 copy number variation, and phenoconversion in 15,000 patients.

Molecular psychiatry - 1 Nov 2024

Patel Jai N, Morris Sarah A, Torres Raul, Rhead Brooke, Vlangos Chris, Mueller Daniel J, Brown Lisa C, Lefkofsky Hailey, Ali Muneer, De La Vega Francisco M, Barnes Kathleen C, Zoghbi Anthony, Stanton Joseph D, Badgeley Marcus A

Abstract excerpt

Pharmacogenomic testing has emerged as an aid in clinical decision making for psychiatric providers, but more data is needed regarding its utility in clinical practice and potential impact on patient care. In this cross-sectional study, we determined the real-world prevalence of pharmacogenomic actionability in patients receiving psychiatric care. Potential actionability was based on the prevalence of CYP2C19 and...

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Source

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Identifiers

PMID: 38783055
DOI: 10.1038/s41380-024-02588-4
PMCID: PMC11541190

Genes

CYP2C19
TG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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