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Article

Atrial Fibrillation Screening According to Genetic Risk: A Secondary Analysis of the Randomized LOOP Study.

Journal of the American College of Cardiology - 20 Jan 2026

Vad Oliver B, Diederichsen Søren Z, Xing Lucas Y, Paludan-Müller Christian, Monfort Laia M, Ahlberg Gustav, Andreasen Laura, Haugan Ketil J, Graff Claus, Højberg Søren, Krieger Derk, Brandes Axel, Køber Lars, Svendsen Jesper H

Abstract excerpt

BACKGROUND: Polygenic risk scores (PRS) hold promise in risk stratification and screening for cardiovascular diseases, including atrial fibrillation (AF). OBJECTIVES: This study investigated the efficacy of AF screening for stroke prevention based on a PRS for AF. METHODS: This prespecified post hoc analysis of the randomized LOOP (Atrial Fibrillation Detected by Continuous ECG Monitoring Using Implantable Loop...

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PMID: 41159983
DOI: 10.1016/j.jacc.2025.09.024

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