Article
Validation of a genetic risk score for atrial fibrillation: A prospective multicenter cohort study.
PLoS medicine - 1 Mar 2018
Muse Evan D, Wineinger Nathan E, Spencer Emily G, Peters Melissa, Henderson Riley, Zhang Yunyue, Barrett Paddy M, Rivera Steven P, Wohlgemuth Jay G, Devlin James J, Shiffman Dov, Topol Eric J
Abstract excerpt
BACKGROUND: Atrial fibrillation (AF) is the most commonly encountered arrhythmia and is associated with an elevated risk of stroke. Improving the identification of patients with the highest risk for AF to enable appropriate surveillance and treatment, if necessary, is critical to reducing AF-associated morbidity and mortality. Multiple common single nucleotide polymorphisms (SNPs) are unequivocally associated...
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