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Article

Twelve-single nucleotide polymorphism genetic risk score identifies individuals at increased risk for future atrial fibrillation and stroke.

Stroke - 1 Oct 2014

Tada Hayato, Shiffman Dov, Smith J Gustav, Sjögren Marketa, Lubitz Steven A, Ellinor Patrick T, Louie Judy Z, Catanese Joseph J, Engström Gunnar, Devlin James J, Kathiresan Sekar, Melander Olle

Abstract excerpt

BACKGROUND AND PURPOSE: Atrial fibrillation (AF) is prevalent and there is a clinical need for biomarkers to identify individuals at higher risk for AF. Fixed throughout a life course and assayable early in life, genetic biomarkers may meet this need. Here, we investigate whether multiple single nucleotide polymorphisms together as an AF genetic risk score (AF-GRS) can improve prediction of one's risk for AF....

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Source

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Identifiers

PMID: 25123217
DOI: 10.1161/STROKEAHA.114.006072
PMCID: PMC4346099

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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