Article
vvv2_align_SE, vvv2_align_PE/vvv2_display: Galaxy-Based Workflows and Tool Designed to Perform, Summarize and Visualize Variant Calling and Annotation in Viral Genome Assemblies.
Viruses - 17 Oct 2025
Flageul Alexandre, Hirchaud Edouard, Courtillon Céline, Carnet Flora, Brown Paul, Grasland Béatrice, Touzain Fabrice
Abstract excerpt
Background: Next-generation sequencing (NGS) analysis of viral samples generates results dispersed across multiple files-genome assembly, variant calling, and functional annotations-making integrated interpretation challenging. Variants often yield numerous low-frequency or non-significant variants, yet only a small fraction are biologically relevant. Virologists must manually sift through extensive data to...
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