LazypipeX: Customizable Virome Analysis Pipeline Enabling Fast and Sensitive Virus Discovery from NGS data

Abstract excerpt

<h4>ABSTRACT</h4> Metagenomic next-generation sequencing (mNGS) is pivotal for detecting known and novel viruses in diverse samples; however, its efficacy relies on robust bioinformatics pipelines. We present LazypipeX with multiple advanced features, including flexible annotation strategies that can be adjusted to match different datasets and applications. Using a synthetic benchmark, we show that a simple two-r...

Topics

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• Genome, Viral
• Hepacivirus
• High-Throughput Nucleotide Sequencing
• HIV
• Influenza A virus
• Metagenomics
• Respiratory viral infections research
• Sequence Analysis, DNA

Identifiers and source

Literature Corpus work

8e734209-fcb7-562c-a92d-b6a588495b11

DOI

10.1101/2025.04.29.651217