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Article

LayerCake: a tool for the visual comparison of viral deep sequencing data.

Bioinformatics (Oxford, England) - 1 Nov 2015

Correll Michael, Bailey Adam L, Sarikaya Alper, O'Connor David H, Gleicher Michael

Abstract excerpt

MOTIVATION: The advent of next-generation sequencing (NGS) has created unprecedented opportunities to examine viral populations within individual hosts, among infected individuals and over time. Comparing sequence variability across viral genomes allows for the construction of complex population structures, the analysis of which can yield powerful biological insights. However, the simultaneous display of sequence...

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PMID: 26153515
DOI: 10.1093/bioinformatics/btv407
PMCID: PMC4626748

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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