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Article

Genetic association analyses of cognitive performance across multi-ancestry older adults: Application of Tobit models.

Journal of Alzheimer's disease : JAD - 1 Dec 2025

Wu Xian, Tsuchiya Inori, Aung Khine Zin, Qiao Qi, Fardo David W, Nelson Peter T, Abner Erin L, James Bryan D, Norris Christopher M, Katsumata Yuriko

Abstract excerpt

BackgroundPrevious studies investigating associations between genetic variants and late-onset Alzheimer's disease (LOAD)-related cognitive functions included primarily European-ancestry individuals and utilized linear models on neuropsychological test scores with ceiling effects.ObjectiveInvestigate associations between LOAD-related single nucleotide polymorphisms (SNPs) and neuropsychological test scores by...

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Identifiers

PMID: 41129700
DOI: 10.1177/13872877251385220
PMCID: PMC12593228

Genes

ADAMTS1
APOE
SHARPIN
TMEM106B

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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