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Article

Maternal organophosphate pesticide exposure in relation to birthweight: Modification by placenta transporter genotype.

Placenta - 1 Dec 2025

Nguyen Duong Q, Hyman Sara, Medley Eleanor, Bozack Anne K, Kahn Linda G, Kannan Kurunthachalam, Guitierrez Alejandra, Aleksunes Lauren M, Rivera-Núñez Zorimar, Cowell Whitney

Abstract excerpt

Exposure to organophosphate pesticides (OPPs) has been linked to adverse birth outcomes, including low birthweight. Maternal biomarkers are commonly used as proxies for fetal exposure, but fetal exposure also depends on placental transport mechanisms. In 240 mother-newborn pairs, we explored how genetic variation in membrane transporters influences the association between maternal OPP concentrations and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41109040
DOI: 10.1016/j.placenta.2025.10.011
PMCID: PMC12822829

Genes

SLC22A11
SLCO2B1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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