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Article

Maternal fine particulate matter exposure, polymorphism in xenobiotic-metabolizing genes and offspring birth weight.

Reproductive toxicology (Elmsford, N.Y.) - 1 Dec 2010

Slama Rémy, Gräbsch Carolin, Lepeule Johanna, Siroux Valérie, Cyrys Josef, Sausenthaler Stefanie, Herbarth Olf, Bauer Mario, Borte Michael, Wichmann H Erich, Heinrich Joachim

Abstract excerpt

We aimed to describe if polymorphisms in xenobiotics-metabolizing genes modify the effect of maternal exposure to fine particulate matter (PM(2.5)) on offspring birth weight. Among newborns from LISA cohort, we tested if polymorphisms of GSTT1, GSTP1, GSTM1, and CYP2D6 genes modified the effect measure of PM(2.5) on term birth weight. Subsequently, we tested if polymorphisms modified the effect of other exposure...

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Source

Identifiers

PMID: 20656020
DOI: 10.1016/j.reprotox.2010.07.001

Genes

GSTP1
GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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