Article
Polymorphisms in ABC transporter genes and concentrations of mercury in newborns--evidence from two Mediterranean birth cohorts.
PloS one - 1 Jan 2014
Llop Sabrina, Engström Karin, Ballester Ferran, Franforte Elisa, Alhamdow Ayman, Pisa Federica, Tratnik Janja Snoj, Mazej Datja, Murcia Mario, Rebagliato Marisa, Bustamante Mariona, Sunyer Jordi, Sofianou-Katsoulis Alphaikaterini, Prasouli Alexia, Antonopoulou Eleni, Antoniadou Ioanna, Nakou Sheena, Barbone Fabio, Horvat Milena, Broberg Karin
Abstract excerpt
BACKGROUND: The genetic background may influence methylmercury (MeHg) metabolism and neurotoxicity. ATP binding cassette (ABC) transporters actively transport various xenobiotics across biological membranes. OBJECTIVE: To investigate the role of ABC polymorphisms as modifiers of prenatal exposure...
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