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Article

Cell painting in HepaRG cells: an interlaboratory reproducibility study.

Toxicological sciences : an official journal of the Society of Toxicology - 1 Dec 2025

Sherer Eric, Chen Wei, Aberasturi Dillon, Sagar Ksheera, Li Yang, Sutake Zachary, Xu Jiaqi, Harris Felix R, Harrill Joshua A, LaRocca Jessica

Abstract excerpt

Traditional toxicological safety assessment relies heavily on the use of animals, and animal-free new approach methodologies (NAMs) are therefore critical for increasing the efficiency and human relevance of chemical hazard screening. Cell Painting, a high-content imaging assay that quantifies phenotypic changes at the cellular level, is an approach that has been widely used for pharmacological discovery...

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PMID: 41081626
DOI: 10.1093/toxsci/kfaf139

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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