Article

Chemical screening of food-related chemicals for human fatty liver risk: Combining high content imaging of cellular responses with in vitro to in vivo extrapolation

2022-06-03

Abstract excerpt

1 Nonalcoholic fatty liver disease (NAFLD) is an increasingly prevalent human disease with accumulating evidence linking its pathophysiology and co-morbidities to chemical exposures. The complex pathophysiology of NAFLD has limited the elucidation of potential chemical etiologies. In this study we generated a high-content imaging analysis method for the simultaneous quantification of sentinel steatosis cellular ma...

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Literature Corpus work: 43bc7097-9c5c-55e4-acba-55e8a38f6526
DOI: 10.1101/2022.06.02.494529

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