Article
The role of 5-hydroxytryptamine receptor 2A (HTR2A) gene polymorphisms in treatment-resistant obsessive-compulsive disorder: a comparative study with other treatment-resistant mental disorders.
BMC psychiatry - 7 Oct 2025
Del Casale Antonio, Gentile Giovanna, Arena Jan Francesco, Modesti Martina Nicole, Zocchi Clarissa, Mancino Serena, De Luca Ottavia, Angeletti Gloria, Ferracuti Stefano, Preissner Robert, Pompili Maurizio, Simmaco Maurizio, Borro Marina
Abstract excerpt
BACKGROUND: This study investigates the role of genetic variations in the 5-Hydroxytryptamine Receptor 2A (HTR2A) gene in subjects with treatment-resistant obsessive-compulsive disorder (TR-OCD), compared to individuals with other treatment-resistant mental disorders (TRMDs). The goal is to explore whether specific HTR2A polymorphisms contribute to distinguishing TR-OCD from other TRMDs, thereby advancing our...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.