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Article

Common variants of HTR3 genes are associated with obsessive-compulsive disorder and its phenotypic expression.

Scientific reports - 12 Sept 2016

Kim Hae Won, Kang Jee In, Lee Sang-Hyuk, An Suk Kyoon, Sohn Sung Yun, Hwang Eun Hee, Lee Su Young, Kim Se Joo

Abstract excerpt

Evidence from literature supports the existence of associations between serotonin-related genetic variants and obsessive-compulsive disorder (OCD), but few studies have explored the involvement of serotonin receptor type 3 genes (HTR3) in OCD. To identify whether HTR3 variability affects an individual's susceptibility to OCD, we examined 10 HTR3 variants in 596 individuals with OCD and 599 controls. A significant...

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Genetic Association Studies
Genetic Predisposition to Disease
Genotype
Haplotypes
Obsessive-Compulsive Disorder

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Receptors, Serotonin, 5-HT3

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Identifiers

PMID: 27616601
DOI: 10.1038/srep32564
PMCID: PMC5018838

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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