Article
Association analysis of SLC6A4 and HTR2A genes with obsessive-compulsive disorder: Influence of the STin2 polymorphism.
Comprehensive psychiatry - 1 Apr 2018
Gomes Chayenne Karine Ferreira, Vieira-Fonseca Tamiris, Melo-Felippe Fernanda Brito, de Salles Andrade Juliana Braga, Fontenelle Leonardo F, Kohlrausch Fabiana Barzotti
Abstract excerpt
BACKGROUND: Obsessive-Compulsive Disorder (OCD) is a complex and chronic disorder characterized by recurrent thoughts and/or repetitive behaviors. Given the potent anti-obsessional effects of the so-called serotonin reuptake inhibitors, genes related to serotonergic system may be well implicated in the etiopathogenesis of OCD. The gene encoding the serotonin transporter (SLC6A4), which shows a variable number of...
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