Article
Genetic Underpinnings of Obsessive-Compulsive Disorder With and Without Tics: Implications of Genetic Heterogeneity on Clinical Management.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Apr 2026
Zouki Jade-Jocelyne, Wu Weng Tong, Stylianakis Anthea, Eapen Valsamma
Abstract excerpt
The exact genetic mechanisms and link between obsessive-compulsive disorder (OCD) and tics/Tourette syndrome are not fully understood. This narrative review aims to summarize the literature examining whether the clinical phenotypes of OCD and OCD + tics (tic-related OCD) represent distinct entities and how this relates to their genetic underpinnings. Systematic searches were conducted in MEDLINE Complete and...
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