Article
The association of HTR2A polymorphisms with obsessive-compulsive disorder and its subtypes: A meta-analysis.
Journal of affective disorders - 1 Oct 2020
Mattina Gabriella Francesca, Samaan Zainab, Hall Geoffrey B, Steiner Meir
Abstract excerpt
BACKGROUND: Genetic risk factors that contribute to obsessive-compulsive disorder (OCD) have yet to be elucidated. Historically, serotonergic dysfunction has been implicated. Evidence from the literature points towards the serotonin receptor 2A gene (HTR2A) as a primary candidate. Our meta-analysis investigated whether polymorphisms in HTR2A are associated with OCD or its subtypes, based on sex and age of onset....
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