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Article

Immune cells as mediators in lipids-colorectal cancer risk: A Mendelian randomization study.

Medicine - 3 Oct 2025

Zhang Xu, Duan Xuchu, Wang Liping, Zhang Jian, Feng Jun, Zhang Cuiping, Yuan Fang

Abstract excerpt

The occurrence and progression of colorectal cancer (CRC) are closely associated with abnormal lipid metabolism and immune regulation in the tumor microenvironment. Lipids are not only essential components of cell membranes but also influence CRC progression by modulating signaling pathways and inflammatory responses. In recent years, Mendelian randomization (MR) analysis, a causal inference method utilizing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41054116
DOI: 10.1097/MD.0000000000044604
PMCID: PMC12499694

Genes

CD80

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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